The cure for type 1 diabetes in dogs

diabetes is a metabolic disease that affects not only humans, but also dogs.It is characterized by causing very high levels of sugar, which compromise the dog's life in the long term, so you must follow a very strict control , which can not miss insulin, basic to the process of glucose metabolism.

In this article of Animals and Pets Online we will explain everything about the cure of type 1 diabetes in dogs , something that the UAB of Barcelona has studied and exhibited.Read more and read more about this interesting study.

The UAB study

In a recent scientific study, completely reversed the diabetes of 5 Beagle dogs with a single injection session was achieved.The study was carried out by researchers at Universitat Autonoma de Barcelona and published in the prestigious magazine Diabetes.

All the dogs used in the research were between 6 and 12 months old at the beginning of therapy gene to which they were subjected.The therapy consisted of introducing vectors (harmless viruses) in the muscle cells of dogs, to allow the expression of insulin and glucokinase in them.

The 2 enzymes produced in the muscles act as a "sensor" of glucose, allowing it to enter the cells of the body and regulating its concentration in the blood.Thus, gene therapy would have allowed muscle cells to replace the function of damaged cells of the pancreas of dogs.

The results

The result was very encouraging , since 4 years after the injection session, the "diabetic" beagles continued to regulate the blood sugar level.They had no episodes of hyperglycemia when eating, nor episodes of hypoglycemia when exercising.Their bodies were able to regulate glucose perfectly without the need for insulin injections or special diets.

Although the results of the team Catalan scientists are very impressive and encouraging, it is still an experimental cure .These results should still be taken with caution because the dogs used in the experiment suffered from chemically induced diabetes to simulate diabetes type 1 of humans, since the latter does not occur naturally in dogs.

Therefore, the genetic therapy used cannot be transferred directly to dogs that have natural or human diabetes.However, possibly It is a first stage to achieve a cure for diabetes.

Future studies are planned to be able to implement this type of genetic therapy in dogs that have natural diabetes, as well as in other companion animals.studies would allow us to think about the adaptation of this type of therapy to humans in the future.

Bibliography

David Callejas, Christopher John Mann, Eduard Ayuso, Ricardo Lage, Iris Grifoll, Carles Roca, Anna Andaluz, Rafael Ruiz-de Gopegui, Joel Montane, Sergio MuÅ „oz, Tura Ferre, Virginia Haurigot, Shangzhen Zhou, Jesus Ruberte, Federico Mingozzi, Katherine High, Felix Garcia and Fatima Bosch- Treatment of Diabetes and Long-term Survival Following Insulin and Glucokinase Gene Therapy-Diabetes 2013 Jan; DB_121113.https://doi.org/10.2337/db12-1113

This article is merely informative, at Animals and Pets Online we have no power to prescribe veterinary treatments or make any diagnosis.We invite you to take your pet to the veterinarian in case he presents any type of condition or discomfort.

If you want to read more articles similar to The cure of type 1 diabetes in dogs , we recommend that you enter our Hereditary Diseases section.

Comments

Types of monkeys and their names

Monkeys are primates classified according to scientific jargon in the Platirrinos or monkeys of the new world and the Cercopitecoideos or monkeys of the old world.The hominoids, which would be primates that have no tail, where man enters. Animals such as orangutan, chimpance, gorilla or gibbons also do not enter the scientific classification of monkeys, since the latter, in addition to having a tail, have a more primitive skeleton and are small animals. Then you can see the scientific classification of monkeys in more detail, where you can distinguish two different parvordenes and a total of six families of monkeys, all this in this article of Animals and Pets Online.The different types of monkeys and their names you can see them below: Classification of the Simiiform infraorder To correctly understand everything about the types of monkeys we must detail that there are a total of 6 families of monkeys grouped in 2 different parvordenes. Parvorden Platyrrhini: This in...

ALL ABOUT THE FEVER IN DOGS

The fever in dogs or fever Canine is an increase in body temperature above normal values, which are between 38 and 39ºC , due, for example, to an infection or inflammation.There are different causes that cause the fever and we can easily measure it with the use of a digital thermometer. Next, in this article of Animals and Pets Online we will explain everything you need to know about fever in dogs, causes, symptoms and treatment to be applied to lower it.That is, if you suspect that your dog may suffer from fever, we recommend you go to your trusted veterinarian to discover the cause that is causing it and the treatment indicated according to your specific case. What temperature is considered fever in dogs? Fever is an excellent defense mechanism of the body .By increasing body temperature, the immune system seeks to destroy the pathogen.Therefore, it is a immune system reaction very beneficial for the dog in the face of an illness. The normal temperature of a dog Th...

Mediterranean rock fish

In the Mediterranean sea coast there is a very rich fauna and diverse.There are surface, medium and deep water fishes.And among the fish that live in the depths of the coast, the Mediterranean rock fish stand out. Many of these fish are masters of camouflage and can adopt an indistinguishable aspect, identical to that of the rock where they are seated.Others live hidden among the cracks and fissures of the underwater rockery. If you continue reading the Animals and Pets Online we will show you the most characteristic rock fish of the Mediterranean . Small size rock fish In the riverside rocks, part of which emerge out of the water, there are several species of small-sized rock fish .Next we will relate the most common ones. Maiden- Coris julis -, beautiful fish of vivid colors. Vaqueta -Serranus scriba -, very common serranido of the shallow waters. Castanuela- Chromis chromis -, a very small fish that lives in small shoals among the rocky shoals. Barriguda- Par...

Common salamanquesa: characteristics

The common salamanquesa ( Tarentola Mauritanica ) is a reptile belonging to the family of geconides ( Gekkonidae ) popularly known as "geckos".They are present in the Iberian Peninsula, Italy and many other countries.Due to their curious morphology, Some people wonder, is salamanquesa poisonous? The truth is that no, it is a totally harmless animal . In this Animals and Pets Online file we will show you everything you need to know about the common salamanquesa: origin, characteristics, habitat , food or reproduction.Read more, you'll be surprised to learn more about this little reptile! Origin of the common salamanquesa The salamanquesa is native to the western Mediterranean , although it is currently scattered around the world, mainly due to commercial activities, which have moved it to places as far away and exotic as Africa or America.Also by human mediation I reach the Balearic Islands and the Azores.But in addition, the salamanquesa has been able to adap...

Cetaceans - Meaning, Types and Features

The cetaceans are the marine animals most famous for their presence in ancient tales and legends.They are animals that have always aroused great interest on the part of the human being.These animals, in general, are great strangers that, little by little, are disappearing without, apparently , let's do nothing. In this article of Animals and Pets Online we will talk about cetaceans, which are, their characteristics, where they live and other curiosities .Do you want to know more about these inhabitants of the sea depths? Keep reading! What are cetaceans? The order of the cetaceans is composed of two suborders, the myxicets, formed by the bearded whales, and that of the odontocetes, composed of cetaceans with teeth, such as sperm whales, dolphins and killer whales. The evolution of the cetaceans has resulted in a similarity between these two living suborders, being the result of evolutionary convergence.The common structural characteristics between the two groups, suc...

How to care for a cat with a broken hip

My kitten, we do not know if she suffered a blow or fell hit, the report is that she ran her back a bit, she has no owner recognizes me because I give her to decommission at specific times, she does not attack but she defends herself it is not allowed to touch it has been almost impossible to grab it to place it in the transporter covering its head, now it is in my house to build a shelter it hides under a sofa and makes its needs but I do not see it eat I think it takes water this happened on 22/1 and today is 1/28/2019, they have dared me but I have no experience with animals that are not domesticated and that do not let themselves be touched, it is very intelligent, it hides recognizes the place and I do not know if I should leave it there, I put the sanitary stones and she goes and does her needs and retires down from the sofa I have her fenced, and for now when she is seen I see her well, she does not take the medication for pain and to solidify her bones, but neither does she com...

Small dogs ideal for children

When we want to adopt a dog we must take into account several factors.One very important, if we have Children in our home, will be to welcome a dog that is patient and gets along with the little ones and supports without aggression the mischief that the children's minds are able to machine. If we do not have a very spacious and This factor also counts, the solution will be to adopt a dog of small size.Always informing our son of how to play with him so that he does not get to hurt him.Remember that the adoption of dogs teaches your children values, responsibility and rapport. In ExpertAnimal we will show you some suitable breeds that combine both factors, discover the small dogs ideal for children .However, remember that many of the dogs in the shelters (whether mestizo or breed) they are equally appropriate for a child, im It is important that both be happy together.Continue reading: Small dogs, great character It is well known that the idiosyncrasy of most small dogs is...

12 animals of Patagonia that you should know

Animals of Chilean and Argentine Patagonia Generally, Patagonia is usually "divided" into two large areas or regions: the coastal or coastal zone , which is cleared by the Atlantic Ocean on the Argentine side and the Ocean Pacific, in Chile, and the continental or Andean-Patagonian region that includes the most central regions, with predominantly desert climates, up to the Andes Mountains, with a great predominance of humid and glacial forests. In addition to the differences in the landscape, it is also possible to note that biodiversity is usually different in these regions.In the coastal region, we observe a clear predominance of fish, birds and aquatic mammals, while in the area continental land mammals and species adapted to freshwater bodies, mainly lakes and lagoons stand out. As in both regions, we find several locations with similar microclimates and environmental conditions in both Chilean Patagonia and the argenti na, it is possible to find many species tha...

My cat is very possessive of me, what should I do?

As with humans, cats can feel jealous and be very possessive of their tutors.While some people see jealousy as a demonstration of love, the truth is that a possessive cat can be a risk to themselves, their tutors and others people around them.Many times we see that a possessive feline becomes aggressive or hides when visitors arrive, or when a new family member is not properly introduced before entering their territory, which makes it impossible for a healthy coexistence in the home. Do you feel that your cat is jealous and doesn't want to share your attention with others? So, we invite you to continue reading this Animals and Pets Online article to know what to do if your cat is very possessive of you . Why are cats possessive of their owners? To answer this question we can think of human behavior itself.When a person feels jealous of someone, it is usually a sign that he is afraid of losing his attention or be replaced by another person, for a job or for a pet.This me...

Why do they say cats have 7 lives?

How many times have you not heard and used the expression? " Cats have 7 lives "?.There are multiple theories that explain this well-known myth.Most, as esoteric and ancient as interesting and other scientists who refute the myth of the 7 lives, but we know They talk about the great strength of these feline creatures. The belief that cats have 7 lives is popular in practically the whole world.In fact, in Anglo-Saxon countries like England, they are so cat lovers, that generously they have donated two more opportunities, reaching 9 lives. If you want to know where this expression comes from and know the different hypotheses, continue reading this article of Animal Expert, where we will reveal the mystery that revolves around the supposed 7 lives of cats. An ancestral belief The belief that cats have 7 lives is as old as the Egyptian civilization .In Egypt, the first theory that has to do with the Eastern and spiritual concept of reincarnation was born.Reincarnation...

Animals and Pets Online

Search This Blog