Skip to main content

The cure for type 1 diabetes in dogs

The cure for type 1 diabetes in dogs

diabetes is a metabolic disease that affects not only humans, but also dogs.It is characterized by causing very high levels of sugar, which compromise the dog's life in the long term, so you must follow a very strict control , which can not miss insulin, basic to the process of glucose metabolism.

In this article of Animals and Pets Online we will explain everything about the cure of type 1 diabetes in dogs , something that the UAB of Barcelona has studied and exhibited.Read more and read more about this interesting study.

The UAB study

In a recent scientific study, completely reversed the diabetes of 5 Beagle dogs with a single injection session was achieved.The study was carried out by researchers at Universitat Autonoma de Barcelona and published in the prestigious magazine Diabetes.

All the dogs used in the research were between 6 and 12 months old at the beginning of therapy gene to which they were subjected.The therapy consisted of introducing vectors (harmless viruses) in the muscle cells of dogs, to allow the expression of insulin and glucokinase in them.

The 2 enzymes produced in the muscles act as a "sensor" of glucose, allowing it to enter the cells of the body and regulating its concentration in the blood.Thus, gene therapy would have allowed muscle cells to replace the function of damaged cells of the pancreas of dogs.

The results

The result was very encouraging , since 4 years after the injection session, the "diabetic" beagles continued to regulate the blood sugar level.They had no episodes of hyperglycemia when eating, nor episodes of hypoglycemia when exercising.Their bodies were able to regulate glucose perfectly without the need for insulin injections or special diets.

Although the results of the team Catalan scientists are very impressive and encouraging, it is still an experimental cure .These results should still be taken with caution because the dogs used in the experiment suffered from chemically induced diabetes to simulate diabetes type 1 of humans, since the latter does not occur naturally in dogs.

Therefore, the genetic therapy used cannot be transferred directly to dogs that have natural or human diabetes.However, possibly It is a first stage to achieve a cure for diabetes.

Future studies are planned to be able to implement this type of genetic therapy in dogs that have natural diabetes, as well as in other companion animals.studies would allow us to think about the adaptation of this type of therapy to humans in the future.

The cure for type 1 diabetes in dogs

Bibliography

David Callejas, Christopher John Mann, Eduard Ayuso, Ricardo Lage, Iris Grifoll, Carles Roca, Anna Andaluz, Rafael Ruiz-de Gopegui, Joel Montane, Sergio MuÃ… „oz, Tura Ferre, Virginia Haurigot, Shangzhen Zhou, Jesus Ruberte, Federico Mingozzi, Katherine High, Felix Garcia and Fatima Bosch- Treatment of Diabetes and Long-term Survival Following Insulin and Glucokinase Gene Therapy-Diabetes 2013 Jan; DB_121113.https://doi.org/10.2337/db12-1113

This article is merely informative, at Animals and Pets Online we have no power to prescribe veterinary treatments or make any diagnosis.We invite you to take your pet to the veterinarian in case he presents any type of condition or discomfort.

If you want to read more articles similar to The cure of type 1 diabetes in dogs , we recommend that you enter our Hereditary Diseases section.

Comments

Popular posts from this blog

Common diseases of the pug or carlino dog

The pug or carlino dogs , due to their anatomical peculiarities, they have a special predisposition to suffer certain diseases, conditions that you should know to guarantee their health as much as possible.That is why, in this article of Animals and Pets Online we will know more thoroughly the pathologies that affect the carlinos. Although we will go on to enumerate the diseases that can suffer (all races have different predisposition to certain diseases), it is a breed that keeping up to date with its veterinary reviews and taking care of it, usually enjoys good In addition, they have an exceptional character, being very affectionate and playful.Read on and discover the most common diseases of the pug or carlino dog . Brachycephalic Syndrome Brachycephalic breeds such as the pug dog are characterized by having a round head and a very short snout , in addition to quite outgoing eyes.Taking into account these characteristics, many of the pathologies that may affect you are rel...

How are cats born? - BIRTH AND BIRTH WITH VIDEO!

Do you want to know how those born? cats? To begin with, we must emphasize that cats are able to have offspring for a good part of the year.Kittens come into the world after about two months of gestation and are born in a delivery that is usually fast and uncomplicated. In this article of Animal Expert we will explain how cats are born so that, as caregivers, we can identify if there is any alteration of normality.In that case it is very important that we contact the vet, since kittens are very vulnerable. At what time of year do cats breed? Before going on to explain how cats are born we should know that cats are seasonal polystrics .This means that they have a period of heat determined by the amount of sunlight.the days begin to get longer the cats will start their zeal and this will not remit until, again, the incidence of light is less. The symptoms of heat include meowing insistent in a high tone, rubbing against our legs, elevation of the pelvis to show the genitals ...

My dog ​​has a transparent flow

Outside the period of heat or, if necessary, childbirth or postpartum, It is not usual for female dogs to have vaginal discharge of discharge, therefore, their appearance may be a source of concern for caregivers, since a bloody flow may be indicative of a serious uterine infection called pyometra.But, if a dog has a transparent or white flow, we can face other causes such as those explained in this article of Animals and Pets Online.Keep reading and discover why your dog presents transparent secretion . The flow in the bitches Before explaining why a dog has a transparent flow, we will talk about the flows that can occur in dogs in a usual way.They are the following: Pinkish flow : This color is typical of the beginning of the estrous cycle and varies between light pink, watermelon, dark pink and even yellowish tones. Bloody flow : more than flow it would be a more or less thick secretion, with a bad smell and pus, which usually indicates an open type pyometra , unl...

The 10 most famous cats in the cinema, do you remember them?

The cat is one of the animals that during more time has lived with the human being.Maybe because of this, he has appeared in countless stories, novels, films and television series.For that reason, in this article, we will share with you names of famous Disney cats, movies and its meaning. So, if you are a lover of cats and of the seventh art, in this post of Animals and Pets Online we review the most famous cats of the cinema .lose! 1.Garfield Garfield, one of the most well-known feline characters, is a lazy and comilon cat , who loves lasana and hates Mondays.This British orchard sorthair breed lives in a typical American house, with its owner, Jon, and the other pet of this, Oddie, a bonachon dog on the side of little intelligent. We could see Garfield for the first time in the comics , although due to its popularity, two movies have been shot in his honor, in which the protagonist is made by computer. 2.Isidoro In addition to the adventures of Garfield, the feats o...

What pet to give to a child?

A pet is not a toy, but if it is a good pet For children, the child can play with her and enjoy her company.When choosing which pet to give to a child, several factors will influence for a sensible choice. The first factor will be the age of the child and his temperament .An overactive child will need a different pet than a more gentle-natured child.Or a ten-year-old child can enjoy a larger range of pets, than a child of four. After determining the age and way of being of the child, we must assess other very important factors: the economy of the home, space, time available, if there is a garden, and the environment.A rural environment is not the same as a large city.Assessing all these various factors, in ExpertAnimal we will advise you what pet give away au n nino to make you happy. Before adopting There are other many pets that can be given to a child, but I prefer to play very safe cards for both the animal and the baby's well-being. If the child shows prefer...

The Wolf's Feeding

The wolf or Canis Lupus is a carnivorous mammal .Also, it is one of the most controversial animals because of its wild beauty and because many people continue to consider them a threat. This animal is a carnivorous mammal with a great capacity to adapt to different Ecosystems: However, the wolf, although carnivorous, does not eat meat.If you want to find out what the feeding of the wolves consists of, do not forget to read this article of Animals and Pets Online. The wolf Before we go into the feeding of the wolf, we will make a general review of its characteristics.We have already seen that it is a carnivorous mammal, but there is much more to tell about them. The length of a wolf is usually around between one and two meters .Its height to the shoulder averages between 60 and 90 centimeters .As for weight, a size wolf half round the 50 kilos . Its fur is two layers , a stronger and stronger exterior whose function is to protect the inner layer, the which is thinner and...

How to care for an epileptic cat

Epilepsy is not an exclusive disease of the human being, dogs and cats also suffer , being in these small felines much more common than we might initially think, which is due to numerous causes ranging from genetic inheritance to various physical problems. Symptoms of epilepsy in cats are very similar to which a human could experience, and although the most characteristic is the seizure, in the feline we can also observe other signals that prepare us to provide the necessary assistance. While it is true that a feline that presents This disease will necessarily require various veterinary care, there are also certain recommendations that we must adopt at home.In this article of Animal Expert we show you how to care for an epileptic cat in order to offer you the best quality of possible life. Recognizing the symptoms of epilepsy in cats Epilepsy in cats is a disease that becomes evident when our pet suffers a spontaneous seizure , however, to be prepared to provide all the necess...

What is a stereotypy in animals?

Especially in the zoo, in animal shelters or in small enclosures and not We can see that these are the stereotypes in animals: These are repetitive actions that the animal carries out without a specific purpose , very clear examples they are the dogs that spin on themselves without stopping, rocking or barking.Sometimes it can be related to a mental problem although we usually talk about serious situations of stress that lead to stereotypy. Do you want to know more things about it? Discover what a stereotypy is in animals and how or why it happens in this complete Animals and Pets Online article. Why it happens? As we have mentioned, stereotypes are repetitive movements that are consequences of stress and usually occur in animals that live in captivity such as shelter dogs, zoo animals etc. The main reason for that happening is the inability to satisfy their natural behavior either due to lack of space, food, a drastic change in their life or poor physical activity.Stere...

Tips for the first days of a cat at home

1.Be patient and know how to respect the process of adapting the cat Before telling you all our tips for the first days of the cat at home, we want to re-emphasize the importance of respecting the process of adapting your new companion.No species is able to adapt instantly to a new reality , because adaptation is just a process and each individual requires their own time to carry it out. The arrival in a new home is a totally new experience for any cat., remember to have patience and dedication during the first days of the cat at home.At first, it is completely natural that the pussy is shy, confused and even somewhat fearful against this unknown environment and all its new stimuli.Therefore, it is possible that this large part of the day hidden and avoid contact with other people or animals. How long does it take a cat to adapt to a new house? It will depend on the personality of ca Give cat and the environment offered by his tutors, so you will need to know how to wait a...

Why does my rat bite me?

There are people who like to have rats as a pet.Normally such animals They have the same affable and affectionate behavior with the person who adopts them as any other pet.They are very intelligent animals. However, sometimes the pet, whatever the species, tends to bite. There are several types of bites that we should know how to interpret . In this article we will focus on biting rats and answer the question: Why does my rat bite me? In ExpertAnimal we will inform you about it, its possible causes and solutions. The meaning of bites Animals demonstrate many things by grading their bites, and the rat is no stranger to this rule.Before asking you why does my rat bite me? you should know that when they are puppies while playing with their parents , or with us, animals gently bite pretending to fight. It's the same thing brothers do when they fight over the sofa or the bed, while they shout, laugh and cry without continuity solution.It is a game, but a game of domination...