The cure for type 1 diabetes in dogs

diabetes is a metabolic disease that affects not only humans, but also dogs.It is characterized by causing very high levels of sugar, which compromise the dog's life in the long term, so you must follow a very strict control , which can not miss insulin, basic to the process of glucose metabolism.

In this article of Animals and Pets Online we will explain everything about the cure of type 1 diabetes in dogs , something that the UAB of Barcelona has studied and exhibited.Read more and read more about this interesting study.

The UAB study

In a recent scientific study, completely reversed the diabetes of 5 Beagle dogs with a single injection session was achieved.The study was carried out by researchers at Universitat Autonoma de Barcelona and published in the prestigious magazine Diabetes.

All the dogs used in the research were between 6 and 12 months old at the beginning of therapy gene to which they were subjected.The therapy consisted of introducing vectors (harmless viruses) in the muscle cells of dogs, to allow the expression of insulin and glucokinase in them.

The 2 enzymes produced in the muscles act as a "sensor" of glucose, allowing it to enter the cells of the body and regulating its concentration in the blood.Thus, gene therapy would have allowed muscle cells to replace the function of damaged cells of the pancreas of dogs.

The results

The result was very encouraging , since 4 years after the injection session, the "diabetic" beagles continued to regulate the blood sugar level.They had no episodes of hyperglycemia when eating, nor episodes of hypoglycemia when exercising.Their bodies were able to regulate glucose perfectly without the need for insulin injections or special diets.

Although the results of the team Catalan scientists are very impressive and encouraging, it is still an experimental cure .These results should still be taken with caution because the dogs used in the experiment suffered from chemically induced diabetes to simulate diabetes type 1 of humans, since the latter does not occur naturally in dogs.

Therefore, the genetic therapy used cannot be transferred directly to dogs that have natural or human diabetes.However, possibly It is a first stage to achieve a cure for diabetes.

Future studies are planned to be able to implement this type of genetic therapy in dogs that have natural diabetes, as well as in other companion animals.studies would allow us to think about the adaptation of this type of therapy to humans in the future.

Bibliography

David Callejas, Christopher John Mann, Eduard Ayuso, Ricardo Lage, Iris Grifoll, Carles Roca, Anna Andaluz, Rafael Ruiz-de Gopegui, Joel Montane, Sergio MuÅ „oz, Tura Ferre, Virginia Haurigot, Shangzhen Zhou, Jesus Ruberte, Federico Mingozzi, Katherine High, Felix Garcia and Fatima Bosch- Treatment of Diabetes and Long-term Survival Following Insulin and Glucokinase Gene Therapy-Diabetes 2013 Jan; DB_121113.https://doi.org/10.2337/db12-1113

This article is merely informative, at Animals and Pets Online we have no power to prescribe veterinary treatments or make any diagnosis.We invite you to take your pet to the veterinarian in case he presents any type of condition or discomfort.

If you want to read more articles similar to The cure of type 1 diabetes in dogs , we recommend that you enter our Hereditary Diseases section.

Comments

Angora rabbit care

If you are thinking of adopting an Angora rabbit , in This article from Animals and Pets Online we will explain the basic care of these cute bunnies. The Angora rabbit is a variety of the domestic rabbit, so its care is very similar.It is believed that its origins are in Turkey, where they were exploited for their fur. The fur differentiates them and that's why their care is very important.If you don't have time to brush and take care of your Angora rabbit we recommend Be responsible and consider it before taking it home. Basic care of Angora rabbit There are four varieties of Angora rabbit: English Angora rabbit French Angora rabbit Angora rabbit giant Angora saten rabbit Between the different varieties there are differences in size and color of the fur, but in terms of care they do not vary in excess. Everyone needs good food, regular exercise and good care of the fur .With these spots covered our little rabbit will grow strong and healthy. They are...

AIR ANIMALS - Examples and characteristics

Flying is one of the ways animals have to move , but not everyone can do it.To fly it is necessary to have physical characteristics that allow the flight.The human being, through the observation of aerial animals, has taken centuries to create a machine that flies, for example, as a bird. Only a few groups of animals have the real ability to fly, although if we see it from the perspective of the species, most of the animal species that exist on the planet fly, insects.In this article of Animal Expert we will know which are the aerial animals , their characteristics and some examples. What are air animals? Air animals are those that use flight as a mechanism of locomotion.For some animals this is their only way of moving but many others use it as an escape route in the presence of a predator. Certain animals spend the majority of their lives flying, performing all their vital functions in the air: eating, interacting with their environment and living or reproducing.For them, f...

Types of monkeys and their names

Monkeys are primates classified according to scientific jargon in the Platirrinos or monkeys of the new world and the Cercopitecoideos or monkeys of the old world.The hominoids, which would be primates that have no tail, where man enters. Animals such as orangutan, chimpance, gorilla or gibbons also do not enter the scientific classification of monkeys, since the latter, in addition to having a tail, have a more primitive skeleton and are small animals. Then you can see the scientific classification of monkeys in more detail, where you can distinguish two different parvordenes and a total of six families of monkeys, all this in this article of Animals and Pets Online.The different types of monkeys and their names you can see them below: Classification of the Simiiform infraorder To correctly understand everything about the types of monkeys we must detail that there are a total of 6 families of monkeys grouped in 2 different parvordenes. Parvorden Platyrrhini: This in...

Animals with exoskeleton - Names and examples

The body of the largest vertebrate animals is not a mystery to most of people: it is known that it has a skeleton, internal vital organs (heart, brain, etc.), a dermis of variable and organ characteristics through which the five senses are manifested, among other characteristics. However, have you wondered what the invertebrate morphology is like? Then you need to know all about the animals with exoskeleton, names and examples. Don't miss this Animals and Pets Online article! What is the exoskeleton? The exoskeleton is an external structure that covers the body of various animals, including arthropods.It is characterized by being resistant but flexible .This structure It consists of different substances depending on the subfile to which the animal belongs: chitin for insects and fungi, calcium in mollusks and corals or silica in diatoms among other components. In turn, the exoskeleton is formed by three structures : Cuticle : non-cellular layer secreted by the hyp...

Differences between donkey and donkey

Taxonomy or classification of animals can, in many cases, give rise to numerous doubts, since sometimes we are not able to identify if two different nomenclatures refer to the same animal or if instead it is a species and subspecies, for example. Some Animals are known by similar names but are part of different species, others can instead be called by several clearly different names and still be the same species, therefore, there are multiple cases that can confuse us and need to be clarified./p> Surely on some occasion you have wondered what are the differences between donkey and donkey , and in this article of Animals and Pets Online we answer your questions. What differentiates an ass from a donkey? When we talk about donkeys we can all evoke the image of an animal with characteristic long ears and tail endowed with great fur, which has traditionally been expanded as a pack animal.Well, when we talk about donkeys, although we may not know this fact, we are talking about...

Pneumonia in dogs - Contagion, care and treatment

Surely you've ever heard of pneumonia, a disease that our dogs may also suffer.In this article of Animals and Pets Online we will review their symptomatology so that you can recognize it and thus transfer your dog to the veterinarian, who, as always, will be responsible for confirming the diagnosis and establishing guidelines for proper care and treatment . Keep reading this article from Animals and Pets Online to learn more about pneumonia in dogs, infection, symptoms and treatment You can't miss it! What is pneumonia? Basically, pneumonia is a inflammation of the lungs , caused by a variety of causes ranging from infectious agents, such as bacteria, to parasites, foreign bodies or allergens.classified according to the area of the lung that affect, according to the predominant cell class, the cause and the type of reaction they cause in the lung.It is the veterinarian in charge of refining the diagnosis to be able to apply the most appropriate treatment. The ...

Diclofenac for dogs - Dosage and uses

The diclofenac sodium is the active substance of a a well-known drug and used under the trade name of Voltaren or Voltadol.It is a product that is used to fight pain .Has your veterinarian prescribed it for your dog? Do you have questions about its uses or doses? In this article of Animals and Pets Online we will talk about diclofenac for dogs , how this drug is used in veterinary medicine and what aspects are important to consider for its use As we always insist, this and any other medication can only be administered to a dog by veterinary prescription . Is diclofenac bad for dogs? Diclofenac is an active substance included in the group of non-steroidal anti-inflammatories , that is, those commonly known as NSAIDs.They are products that are prescribed for pain relief, especially related to bone joint problems .Diclofenac can be used for dogs as long as it is prescribed by the veterinarian. Veterinary use of diclofenac Diclofenac for pain in dogs is used in veterinary me...

Dog breeds not recognized by the FCI

The FCI is the worldwide canine organization that approves pedigree dogs.There are several dog breeds not recognized by the FCI , even if they meet all the requirements to be considered "pure" breeds from the phylogenetic point of view. In this Animals and Pets Onlinet article We explain to you what these breeds are and why they are not recognized by the Federation Cynologique Internationale . Do not forget that the breed of the dog is not important unless you want to participate in morphology competitions canine.Read more: In many cases, breeds are not recognized by the FCI because they do not have a detailed written standard .In other cases because they do not meet the requirements established by the FCI.And in other cases, simply because no canine person or organization has bothered Evade the procedure so that these races are recognized by the FCI. It is also possible that political aspects outside the canine organizations have prevented the international diffu...

Why is my cat very aggressive with other cats?

Did you know that aggressiveness Is it one of the most frequent problems in cats? Although obviously not for that reason we must fall into the error of associating cats with aggressiveness, since they are really domestic animals whose behavior is usually very calm.However, a cat is not a dog and therefore does not present the same level of sociability.A cat does not have to accept another cat, on many occasions, it does not even accept the presence of members of the human family in the corners that he considers to be his exclusive domain. These characteristics make up the genuine character of felines, which can sometimes become problematic.In this article of Animals and Pets Online we explain why your cat is very aggressive with other cats and how to act. Why aggression among cats? Have you decided to host more than one cat at home? This can be a good option, since each one will benefit from the presence of the other but, it also increases the risk that cats can develop aggr...

Caring for rainbow fish

The Melanotaenia boesemani , known as a rainbow fish, it is a small fish of lively color from the lakes of Indonesia and New Guinea, but currently distributed throughout the world in captivity.The bright colors of this species, which mix the blue, violet, yellow, red and white, have made it a favorite for home aquariums, where they stand out for their beauty and fast movements when swimming. If you are thinking of adopting one or more of these specimens, you need to know everything related to the comforts that you must offer them, so ExpertAnimal presents this article about the care of rainbow fish . Rainbow Fish Feeding The rainbow is omnivorous and quite gluttonous, so finding food for it will not be a problem.It is recommended to vary dry food with live prey small size.In this way you can offer everything from flakes and granulated food, to larvae and live artemias.Of course, if you do not find live food you can replace it with one that is frozen. These fish do not...

Animals and Pets Online

Search This Blog