The cure for type 1 diabetes in dogs

diabetes is a metabolic disease that affects not only humans, but also dogs.It is characterized by causing very high levels of sugar, which compromise the dog's life in the long term, so you must follow a very strict control , which can not miss insulin, basic to the process of glucose metabolism.

In this article of Animals and Pets Online we will explain everything about the cure of type 1 diabetes in dogs , something that the UAB of Barcelona has studied and exhibited.Read more and read more about this interesting study.

The UAB study

In a recent scientific study, completely reversed the diabetes of 5 Beagle dogs with a single injection session was achieved.The study was carried out by researchers at Universitat Autonoma de Barcelona and published in the prestigious magazine Diabetes.

All the dogs used in the research were between 6 and 12 months old at the beginning of therapy gene to which they were subjected.The therapy consisted of introducing vectors (harmless viruses) in the muscle cells of dogs, to allow the expression of insulin and glucokinase in them.

The 2 enzymes produced in the muscles act as a "sensor" of glucose, allowing it to enter the cells of the body and regulating its concentration in the blood.Thus, gene therapy would have allowed muscle cells to replace the function of damaged cells of the pancreas of dogs.

The results

The result was very encouraging , since 4 years after the injection session, the "diabetic" beagles continued to regulate the blood sugar level.They had no episodes of hyperglycemia when eating, nor episodes of hypoglycemia when exercising.Their bodies were able to regulate glucose perfectly without the need for insulin injections or special diets.

Although the results of the team Catalan scientists are very impressive and encouraging, it is still an experimental cure .These results should still be taken with caution because the dogs used in the experiment suffered from chemically induced diabetes to simulate diabetes type 1 of humans, since the latter does not occur naturally in dogs.

Therefore, the genetic therapy used cannot be transferred directly to dogs that have natural or human diabetes.However, possibly It is a first stage to achieve a cure for diabetes.

Future studies are planned to be able to implement this type of genetic therapy in dogs that have natural diabetes, as well as in other companion animals.studies would allow us to think about the adaptation of this type of therapy to humans in the future.

Bibliography

David Callejas, Christopher John Mann, Eduard Ayuso, Ricardo Lage, Iris Grifoll, Carles Roca, Anna Andaluz, Rafael Ruiz-de Gopegui, Joel Montane, Sergio MuÅ „oz, Tura Ferre, Virginia Haurigot, Shangzhen Zhou, Jesus Ruberte, Federico Mingozzi, Katherine High, Felix Garcia and Fatima Bosch- Treatment of Diabetes and Long-term Survival Following Insulin and Glucokinase Gene Therapy-Diabetes 2013 Jan; DB_121113.https://doi.org/10.2337/db12-1113

This article is merely informative, at Animals and Pets Online we have no power to prescribe veterinary treatments or make any diagnosis.We invite you to take your pet to the veterinarian in case he presents any type of condition or discomfort.

If you want to read more articles similar to The cure of type 1 diabetes in dogs , we recommend that you enter our Hereditary Diseases section.

Comments

Gineta: characteristics and photos

The gine or genetta genetta in European is a feral animal that inhabits the entire Iberian Peninsula and in the southern half of France.There is a theory that the ginads that populate our lands come from Africa, and were introduced by the Saracens in the eighth century, as domestic animals.Another (more modern) theory states that the Romans had ginnets in their homes to keep them free of mice. Roman ginets came from Egypt although they also had domesticated gints in Constantinople.They are tremendously predatory animals, great hunters of rats, mice and snakes. Origin Wild ginetas originally have two origins: Africa and Asia.From there they have colonized other places, basically due to the intervention of man. It was common the presence of ginetas on the Phoenician ships and ships of later cultures .Obviously, by the success in antiquity and some documents that prove it, the gin can be tamed ; however, it can hardly be considered a pet to use if one is adopted. Physical a...

Animals that clean the aquarium

Aquariums tend to get dirty very easily.An excess of food, a direct sun, having excessive plants or algae in the water can make the water cloudy.Getting a pump or a filter is a good idea but we can also turn to fish and other animals that clean the aquarium naturally by feeding on the carron that resides in the bottom sand. In ExpertAnimal we propose a list of animals that clean the aquarium and some basic notes to know if they could fit in your fish tank.Are you ready? Keep reading and discover our proposals to choose the right one: Snails Here are some species of snails that are in general, excellent bottom cleaners of the aquarium, however you should know that they are suitable for saltwater aquariums so they will be a good option if you have saltwater fish: Tectus niloticus This type of snail is certainly large reaching about 15 centimeters so it is recommended for aquariums of superior size.It has high nutritional requirements so it will serve as a potential clea...

Small dogs ideal for children

When we want to adopt a dog we must take into account several factors.One very important, if we have Children in our home, will be to welcome a dog that is patient and gets along with the little ones and supports without aggression the mischief that the children's minds are able to machine. If we do not have a very spacious and This factor also counts, the solution will be to adopt a dog of small size.Always informing our son of how to play with him so that he does not get to hurt him.Remember that the adoption of dogs teaches your children values, responsibility and rapport. In ExpertAnimal we will show you some suitable breeds that combine both factors, discover the small dogs ideal for children .However, remember that many of the dogs in the shelters (whether mestizo or breed) they are equally appropriate for a child, im It is important that both be happy together.Continue reading: Small dogs, great character It is well known that the idiosyncrasy of most small dogs is...

How to deworm canaries? - Internally and externally

The canary is a bird that has been bred in captivity for more of 500 years and is especially appreciated for its pleasant and sweet melodies.It is also a sweet and harmonious bird that enjoys the company of its relatives in a large cage. However, on the sidelines of their diet, one of the main cares that we must offer our canaries is grooming, since otherwise they contract parasites that can be very dangerous for their health. Do you want to know how to deworm canaries? In this article we tell you different methods! What parasites affect the canaries? The parasites are one of the most common diseases in the Canaries, which contract them mainly due to the lack of hygiene in the space where they live.If you have canaries it is of vital importance that you maintain a correct cleaning of their cages and utensils, since certain parasites can even cause them death. The most common parasites that affect these birds are: Mites in the canaries : they can stay in the body of the a...

Common diseases of mandarin diamond

If you are thinking of hosting a Mandarin diamond or you already have one, in addition to its Basic care you should also know some of the most common conditions that this exotic bird can suffer.The Taeniopygia guttata is a very small bird and very appreciated for its appearance and its simple care but, to give it the best quality of life in our home, we must recognize some symptoms and health problems that will indicate when you should go to the veterinarian. Therefore, in this article of Animals and Pets Online we will explain the most common diseases of Mandarin diamond or Timor's zebra diamond, so that you can detect when it is possible that your little pet is having a problem. Constipation One of the most common health problems in these small birds is constipation .Among the signs that will alert us that our partner is suffering from this disorder we will see the following: Difficulty to evacuate Irritated sewer Swollen belly Wrapping Repetitive gestures down ...

Tips for training a golden retriever

Having an untrained dog is wasting the innate learning abilities of the pet and It is probably something that we usually ask when an animal arrives at our home.In the case of the golden retriever the same thing happens, and although it is a breed of dog with an enviable character, it also needs a good training to not only be able to get the best out of it, but also for its owner in order to live in harmony and without added complications. A golden retriever is a very intelligent dog, and if the training is appropriate, normal in they are practically behaving like one more person in the family.In this sense, if you have a golden retriever but you are not an expert in this breed, follow our tips to train a golden retriever that we offer you in Animals and Pets Online so that everything is ulte much easier. Train a golden retriever puppy Training experts say that the highest rate of success in dog training occurs when they start educating them from puppies, something that is quit...

Diclofenac for dogs - Dosage and uses

The diclofenac sodium is the active substance of a a well-known drug and used under the trade name of Voltaren or Voltadol.It is a product that is used to fight pain .Has your veterinarian prescribed it for your dog? Do you have questions about its uses or doses? In this article of Animals and Pets Online we will talk about diclofenac for dogs , how this drug is used in veterinary medicine and what aspects are important to consider for its use As we always insist, this and any other medication can only be administered to a dog by veterinary prescription . Is diclofenac bad for dogs? Diclofenac is an active substance included in the group of non-steroidal anti-inflammatories , that is, those commonly known as NSAIDs.They are products that are prescribed for pain relief, especially related to bone joint problems .Diclofenac can be used for dogs as long as it is prescribed by the veterinarian. Veterinary use of diclofenac Diclofenac for pain in dogs is used in veterinary me...

ALL ABOUT THE FEVER IN DOGS

The fever in dogs or fever Canine is an increase in body temperature above normal values, which are between 38 and 39ºC , due, for example, to an infection or inflammation.There are different causes that cause the fever and we can easily measure it with the use of a digital thermometer. Next, in this article of Animals and Pets Online we will explain everything you need to know about fever in dogs, causes, symptoms and treatment to be applied to lower it.That is, if you suspect that your dog may suffer from fever, we recommend you go to your trusted veterinarian to discover the cause that is causing it and the treatment indicated according to your specific case. What temperature is considered fever in dogs? Fever is an excellent defense mechanism of the body .By increasing body temperature, the immune system seeks to destroy the pathogen.Therefore, it is a immune system reaction very beneficial for the dog in the face of an illness. The normal temperature of a dog Th...

Milbemax in dogs - USES and DOSE

Milbemax in dogs is a antiparasitic widely used by its wide spectrum of action and its effectiveness, in addition to its ease of use when sold as a chewable tablet with chicken flavor, which facilitates the dog to ingest it voluntarily.In this article of Animals and Pets Online we will talk about the action of milbemax in all types of dogs , its dosage, its possible side effects and, also, the precautions that we must take into account.Of course, we must always administer it according to veterinary prescription . What is milbemax for dogs? As we have said, milbemax is a active antiparasitic product against intestinal parasites such as cestodes, also known as flat worms, or nematodes or roundworms.against other non-intestinal nematodes, such as the Angiostrongylus vasorum , whose adult forms are located in the pulmonary arteries and the heart, or the Thelazia callipaeda , which parasites the eyes.be used in the prevention of another nematode, the Dirofilaria immitis or he...

Types of canaries and their names

How many races of canaries are there? At present, more than 30 types of canaries are known , this being the most abundant species of domestic bird in the world with parakeets, although there are many classifications possible, the canary breeds are usually divided into three large groups: Singing canaries : here, we find the most coveted breeds in canariculture, thanks to their incredible ability to learn and play melodies complex and a great variety of sounds.In the next sections we will see the main races of singing canaries. Canaries by color : this, perhaps, is the most basic classification of canaries, based on the color of their feathers.It is divided into subgroups according to the predominant pigments in its plumage, the lipochromic canaries (shades of dominant and recessive white, yellow and red) and the melancholic canaries (colors black, agate, green, bromine, isabela, brown and tona corrugated qualities). The position or position canaries : also called a design or...

Animals and Pets Online

Search This Blog