The cure for type 1 diabetes in dogs

diabetes is a metabolic disease that affects not only humans, but also dogs.It is characterized by causing very high levels of sugar, which compromise the dog's life in the long term, so you must follow a very strict control , which can not miss insulin, basic to the process of glucose metabolism.

In this article of Animals and Pets Online we will explain everything about the cure of type 1 diabetes in dogs , something that the UAB of Barcelona has studied and exhibited.Read more and read more about this interesting study.

The UAB study

In a recent scientific study, completely reversed the diabetes of 5 Beagle dogs with a single injection session was achieved.The study was carried out by researchers at Universitat Autonoma de Barcelona and published in the prestigious magazine Diabetes.

All the dogs used in the research were between 6 and 12 months old at the beginning of therapy gene to which they were subjected.The therapy consisted of introducing vectors (harmless viruses) in the muscle cells of dogs, to allow the expression of insulin and glucokinase in them.

The 2 enzymes produced in the muscles act as a "sensor" of glucose, allowing it to enter the cells of the body and regulating its concentration in the blood.Thus, gene therapy would have allowed muscle cells to replace the function of damaged cells of the pancreas of dogs.

The results

The result was very encouraging , since 4 years after the injection session, the "diabetic" beagles continued to regulate the blood sugar level.They had no episodes of hyperglycemia when eating, nor episodes of hypoglycemia when exercising.Their bodies were able to regulate glucose perfectly without the need for insulin injections or special diets.

Although the results of the team Catalan scientists are very impressive and encouraging, it is still an experimental cure .These results should still be taken with caution because the dogs used in the experiment suffered from chemically induced diabetes to simulate diabetes type 1 of humans, since the latter does not occur naturally in dogs.

Therefore, the genetic therapy used cannot be transferred directly to dogs that have natural or human diabetes.However, possibly It is a first stage to achieve a cure for diabetes.

Future studies are planned to be able to implement this type of genetic therapy in dogs that have natural diabetes, as well as in other companion animals.studies would allow us to think about the adaptation of this type of therapy to humans in the future.

Bibliography

David Callejas, Christopher John Mann, Eduard Ayuso, Ricardo Lage, Iris Grifoll, Carles Roca, Anna Andaluz, Rafael Ruiz-de Gopegui, Joel Montane, Sergio MuÅ „oz, Tura Ferre, Virginia Haurigot, Shangzhen Zhou, Jesus Ruberte, Federico Mingozzi, Katherine High, Felix Garcia and Fatima Bosch- Treatment of Diabetes and Long-term Survival Following Insulin and Glucokinase Gene Therapy-Diabetes 2013 Jan; DB_121113.https://doi.org/10.2337/db12-1113

This article is merely informative, at Animals and Pets Online we have no power to prescribe veterinary treatments or make any diagnosis.We invite you to take your pet to the veterinarian in case he presents any type of condition or discomfort.

If you want to read more articles similar to The cure of type 1 diabetes in dogs , we recommend that you enter our Hereditary Diseases section.

Comments

Frugivoros Animals - Characteristics and +20 Examples

Frugivorous animals are those that base their diet on the consumption of fruits , or much of what they consume is made up of this type of food.In the animal kingdom, many species are frugivorous, from insects to large mammals. The plants that produce fruits are the angiosperms .In this group, the flowers of the female plants or the female parts of a hermaphrodite plant have an ovary with several ovules that, when fertilized by a sperm, thickens and changes color, acquiring very attractive nutritional qualities for animals. 20% of the known species of Mammals are frugivorous animals, so this type of diet is very significant and important among animals. At first glance, frugivorous animals do not seem to possess distinctive features of animals not frugivoros, even less if they are omnivorous animals that, although they can be feed on many products, its main food is fruit. The main qualities appear along the digestive tract , starting with the mouth or beak.In mammals or o...

Why are flamingos pink?

Flamingos are birds belonging to the genus Phoenicopterus , of which three living species are known, Phoenicopterus chilensis (Chilean flamingo), Phoenicopterus roseus (common flamingo) and Phoenicopterus ruber (pink flamingo) , all of them pink when they are adults. This unique bird of great size and peculiar appearance, is able to travel long distances during the time of migration.They live in wetlands, where they feed and raise their chicks , only one per couple.At birth, the chickens are white-gray with certain black areas of the body but, when they reach adulthood, they acquire a marvel and characteristic pink color. In this article of Animals and Pets Online We will discover how this bird acquires this emblematic bird and solve your doubt about because the flamingos are pink , don't miss it! The color of the birds The color of birds is the result of the accumulation of pigments in intergumentary structures (skin or, mainly, feathers).Birds do not produce a...

Malt for cats - Different uses and how often to offer it

Cats are especially clean animals that spend hours grooming.lick ingest a lot of hair.If you live with a cat, you've sure seen it seen coughing and even vomiting hairballs. That's when some people turn to cat malt , a very useful product of natural origin that improves digestion and intestinal transit of our cat. Discover in Animals and Pets Online everything related to malt for cats, including the necessary doses, at what age It should be offered or information about vomiting.All the benefits of this product below: What is malt? Cat malt is a paste of color similar to honey and denser texture .It consists of vegetable oils and fats, malt extract, fiber, dairy products and yeast mainly.It also often contains dyes, preservatives and vitamins. There are numerous brands in the market with different formats.The most frequent is in the form of a tube of toothpaste.The composition varies slightly according to the brand but the basis is malt extract.Some cats show a prefe...

What do my dog's barks mean

As we know, dogs communicate in many different ways both with each other and with the rest of living beings and some do it so clearly that humans often say that "if you do not need to speak, you already know what you want to tell me and how to do it." It is important to know that Dogs communicate in many ways for example with their smell, their body, with vocalizations and looks, etc.In the case of voice communication, barking is perhaps the most recognizable form of communication in dogs, but they are not the only form since they also shout, snort or snort, grunt and groan. In this new article of Animals and Pets Online we are going to focus on a single aspect of the communication of the canids, the barking.Certainly there are very varied barks but all they have their reason for being.If you want to know what your dog's barking means read on and then you will see the different types and meanings of their barking. Continuous, fast and medium tone barks Dogs use...

Banar my cat at home

When you first think about baning your cat at home, you have a doubt : Do cats bathe? And here comes the false belief that you should never bang a cat, something totally false.Cats if they can bathe , but they don't like it, it's another story.Although it is It is true that if a cat is homemade and has never had any "accident" playing with mud, oil or any other product that seriously soils its fur, with its tongue, the cat can live perfectly without the need for a bath. But cats are playful and we can find ourselves in the situation where our cat suddenly shows up with large spots of dirt on his body, something that he just won't be able to clean and that's when he needs our help.Dogs should not be bathed before 3 months of age, if we bathe them at an early age we can endanger their health since their defenses are not yet fully developed. Then, in this article of Animals and Pets Online we will give you some guidelines and tips on how to banar a your ca...

Seizures in cats - Causes and what to do

At ExpertAnimal we know that taking care of your cat's health is essential for him to have the quality of life that he deserves so much.Felines are usually strong and resistant animals, unlikely to get diseases.However, this does not mean that you should lower your guard against any strange behavior. That a cat convulsion is a situation that generates high levels of discomfort in their human companions, because it is a very distressing situation of presence.It is also for our feline, who does not understand what happens to him.However, keep calm, help him in the moment and go to your veterinarian is the unspeakable way to help him.That is why we want to talk to you about seizures in cats, causes and what to do when they occur.how to deal with this problem in the most appropriate way. What are seizures? It is a series of repetitive and uncontrollable movements , produced by an alteration of the normal functioning of brain activity.A simple way to explain the process is to...

Australian cattle dog or Australian sheepdog: characteristics and photos

The Australian cattle herder en also known as australian cattleman or australian cattle dog .It also receives two different names depending on the type of fur it develops: blue heeler or red heeler .This dog has incredible skills for training, grazing and physical exercise being a prominent dog in the different canine sports. The cattle dog is an excellent dog but is not a dog for any owner .Its great physical, mental stimulation and educational needs make it practically exclusive for people experienced in dog ownership. In this Animals and Pets Online breed sheet we will tell you everything you need to know if you are considering adopting an Australian cattle herder telling you all about his behavior, the character, the care he needs or how his education should be.Don't forget to comment and share your opinions, keep reading: History of the Australian cattle herder Unlike the Australian sheepdog, the Australian buoy if originated in Australia .The European settler...

How to know what size a mongrel dog will be?

When we talk about a mixed breed dog or mixed breed dog , generally we refer to a dog whose ancestry is unknown and that has typical characteristics of two or more breeds.This is usually the result of a non-selective breeding, but generally fortunate, since a mongrel dog can be exactly as good companion as a dog of a certain breed. Due to numerous factors, although here it is worth highlighting the great genetic variability, there are many advantages of having a mongrel dog and it is important to emphasize this point since unfortunately it is usually grant a lower value to a dog of these characteristics.If you are thinking of adopting a mixed breed dog, you are surely gathering all the necessary information, if you are wondering how to know what size a mongrel dog will be I didn't leave It is to read this article of Animals and Pets Online. Is it possible to know the size of a mongrel dog? Of course, estimating the exact size of a mongrel dog is not an easy task, although ...

ALL ABOUT THE FEVER IN DOGS

The fever in dogs or fever Canine is an increase in body temperature above normal values, which are between 38 and 39ºC , due, for example, to an infection or inflammation.There are different causes that cause the fever and we can easily measure it with the use of a digital thermometer. Next, in this article of Animals and Pets Online we will explain everything you need to know about fever in dogs, causes, symptoms and treatment to be applied to lower it.That is, if you suspect that your dog may suffer from fever, we recommend you go to your trusted veterinarian to discover the cause that is causing it and the treatment indicated according to your specific case. What temperature is considered fever in dogs? Fever is an excellent defense mechanism of the body .By increasing body temperature, the immune system seeks to destroy the pathogen.Therefore, it is a immune system reaction very beneficial for the dog in the face of an illness. The normal temperature of a dog Th...

Dog breeds not recognized by the FCI

The FCI is the worldwide canine organization that approves pedigree dogs.There are several dog breeds not recognized by the FCI , even if they meet all the requirements to be considered "pure" breeds from the phylogenetic point of view. In this Animals and Pets Onlinet article We explain to you what these breeds are and why they are not recognized by the Federation Cynologique Internationale . Do not forget that the breed of the dog is not important unless you want to participate in morphology competitions canine.Read more: In many cases, breeds are not recognized by the FCI because they do not have a detailed written standard .In other cases because they do not meet the requirements established by the FCI.And in other cases, simply because no canine person or organization has bothered Evade the procedure so that these races are recognized by the FCI. It is also possible that political aspects outside the canine organizations have prevented the international diffu...

Animals and Pets Online

Search This Blog