The cure for type 1 diabetes in dogs

diabetes is a metabolic disease that affects not only humans, but also dogs.It is characterized by causing very high levels of sugar, which compromise the dog's life in the long term, so you must follow a very strict control , which can not miss insulin, basic to the process of glucose metabolism.

In this article of Animals and Pets Online we will explain everything about the cure of type 1 diabetes in dogs , something that the UAB of Barcelona has studied and exhibited.Read more and read more about this interesting study.

The UAB study

In a recent scientific study, completely reversed the diabetes of 5 Beagle dogs with a single injection session was achieved.The study was carried out by researchers at Universitat Autonoma de Barcelona and published in the prestigious magazine Diabetes.

All the dogs used in the research were between 6 and 12 months old at the beginning of therapy gene to which they were subjected.The therapy consisted of introducing vectors (harmless viruses) in the muscle cells of dogs, to allow the expression of insulin and glucokinase in them.

The 2 enzymes produced in the muscles act as a "sensor" of glucose, allowing it to enter the cells of the body and regulating its concentration in the blood.Thus, gene therapy would have allowed muscle cells to replace the function of damaged cells of the pancreas of dogs.

The results

The result was very encouraging , since 4 years after the injection session, the "diabetic" beagles continued to regulate the blood sugar level.They had no episodes of hyperglycemia when eating, nor episodes of hypoglycemia when exercising.Their bodies were able to regulate glucose perfectly without the need for insulin injections or special diets.

Although the results of the team Catalan scientists are very impressive and encouraging, it is still an experimental cure .These results should still be taken with caution because the dogs used in the experiment suffered from chemically induced diabetes to simulate diabetes type 1 of humans, since the latter does not occur naturally in dogs.

Therefore, the genetic therapy used cannot be transferred directly to dogs that have natural or human diabetes.However, possibly It is a first stage to achieve a cure for diabetes.

Future studies are planned to be able to implement this type of genetic therapy in dogs that have natural diabetes, as well as in other companion animals.studies would allow us to think about the adaptation of this type of therapy to humans in the future.

Bibliography

David Callejas, Christopher John Mann, Eduard Ayuso, Ricardo Lage, Iris Grifoll, Carles Roca, Anna Andaluz, Rafael Ruiz-de Gopegui, Joel Montane, Sergio MuÅ „oz, Tura Ferre, Virginia Haurigot, Shangzhen Zhou, Jesus Ruberte, Federico Mingozzi, Katherine High, Felix Garcia and Fatima Bosch- Treatment of Diabetes and Long-term Survival Following Insulin and Glucokinase Gene Therapy-Diabetes 2013 Jan; DB_121113.https://doi.org/10.2337/db12-1113

This article is merely informative, at Animals and Pets Online we have no power to prescribe veterinary treatments or make any diagnosis.We invite you to take your pet to the veterinarian in case he presents any type of condition or discomfort.

If you want to read more articles similar to The cure of type 1 diabetes in dogs , we recommend that you enter our Hereditary Diseases section.

Comments

How to know what size a mongrel dog will be?

When we talk about a mixed breed dog or mixed breed dog , generally we refer to a dog whose ancestry is unknown and that has typical characteristics of two or more breeds.This is usually the result of a non-selective breeding, but generally fortunate, since a mongrel dog can be exactly as good companion as a dog of a certain breed. Due to numerous factors, although here it is worth highlighting the great genetic variability, there are many advantages of having a mongrel dog and it is important to emphasize this point since unfortunately it is usually grant a lower value to a dog of these characteristics.If you are thinking of adopting a mixed breed dog, you are surely gathering all the necessary information, if you are wondering how to know what size a mongrel dog will be I didn't leave It is to read this article of Animals and Pets Online. Is it possible to know the size of a mongrel dog? Of course, estimating the exact size of a mongrel dog is not an easy task, although ...

10 reasons to walk your dog

The dog is an animal that needs to walk 2 to 3 times a day, But do you know why that is so? In this article of Animals and Pets Online we will explain why it is so important to walk with your dog, why the garden does not replace the walk and many other things that, perhaps you do not know. Do not forget This is a very important habit that you must carry out on a daily basis.Not doing so can be very harmful for your pet, do not forget it.Keep reading and discover 10 reasons to walk with your dog . 1.They must make their needs The first reason, and the most important , to take a dog for a walk, is to allow him to do his needs until he is satisfied. Apart from puppies that are not yet able to go outside or who are learning to urinate, it is very negative to allow our dog to urinate and defecate at home.In addition to causing a bad smell, we will be creating an unhealthy environment important that can lead to serious health problems in dogs and humans. 2.It allows them to ...

Salmonellosis in rodents

Today rodents have become excellent companion animals and there are numerous people that in their house they have guinea pigs, hamsters, mice, gerbils, squirrels, chinchillas or irons. Rodents are active and sociable pets that although they require care they are easy to keep in good condition, however, they are susceptible of contracting multiple diseases and can even transmit some of them to humans, as is the case of salmonellosis. In this article of Animals and Pets Online we show you how to prevent salmonellosis in rodents. What is salmonellosis? Salmonellosis is a disease caused by the bacteria Salmonella Typhimurium , which is usually found in chickens and their eggs as well as in some reptiles such as turtles. This pathogen is also known as Salmonella Enterica , a term that refers to the intestine since it mainly affects this body area, hence It manifests mainly through diarrhea, vomiting and nausea, not only in humans, since these signs are also visible in infec...

Bach flowers for cats

In the last few years we hear frequent talk of Bach flowers, also applied to our Companion animals.There are more and more numerous cases treated with this therapy, as well as veterinary professionals who are trained in this discipline.In this article of Animals and Pets Online we will focus on cats to discover what Bach flowers are, which These are the benefits and uses they can have for our cats.If you've ever heard of these Bach flowers for cats , you're interested in reading! What are Bach flowers? The 38 extracts of flowers and plants discovered by the English doctor Edward Bach in the early twentieth century are called.This doctor chose plants that acted on different conditions that could experience the human beings, such as fear, sadness, anger or hyperactivity.Prepared these plants in the form of dilutions that conserved with alcohol in a dropper to facilitate their use.Various drops were administered directly several times a day or put in the water or even in t...

What to do if my dog is afraid of rockets?

Remove the dog's fear of rockets It will not always be possible.When we talk about traumas or fears, carrying out a systematic desensitization process with a professional can be very effective, but when we talk about phobias, the process can be lengthened much more and can even be Impossible to treat.However, if there are any tips to reassure you that you can use. These are very useful and simple tricks to carry out, especially if we have not had time to go to the veterinarian or educator canine.Next in ExpertAnimal we explain what to do if your dog is afraid of rockets : Why are dogs afraid of pyrotechnics? It's totally normal for a dog to be scared of loud noises.The survival instinct makes them try to run away or hide to save their lives.In the most serious cases we can also observe Excessive salivation, vomiting, diarrhea, nervousness, tremors and anomalous behaviors. There are three main causes that can make the dog afraid of rockets, firecrackers and firewor...

How to accustom an adult dog to being alone?

I have a French bulldog with 5 years, due to circumstances I have had to take him to the house we have in the countryside (he has lived in an apartment until now) The house and the field where he goes knows them perfectly, since in summer we climb all the weekends week and he likes it a lot.I have brought him his bed, rags, toys etc.He has a lot of outdoor space, but I don't know how he will react and if he can go into a period of depression.Any recommendation, you think he will adapt, that he will be happy in the field ?? thanks Eva Lopez (Editor/a from Expert Expert) 09/13/2017 Hi Joanquin, it all depends on the character of your dog and how close he is to you.Will he live with you? If so, the adaptation will be much faster.In any case, you can start wearing it for a little while every day so that it starts to get used, identify odors and leave your own.As the days go by and you observe their behavior, you can start to increase the time until its complete incorporation.Now, if ...

The 10 most popular cat breeds in the world

1.Persian cat: a conqueror par excellence It is very likely that you have or know someone who owns or simply loves these beautiful and furry cats.It is that Persian cats seem to have been born for success.Not only for their sweet appearance and somewhat good-natured, but also for its noble character and, at the same time, kind and caring.In fact, the Persians are so dear to everyone that, since they began to be registered by the CFA ( Cat Fanciers Association ), in 1871, occupies the first position among the most popular cat breeds in the world.An undeniable conqueror! Although his mantle is really precious, we must be clear that the care of a Persian cat as a pet must necessarily include daily brushing to preserve its good health and avoid the formation of knots in its beautiful fur. 2.Siames: the most affectionate of all Impossible to talk about Siamese cats without remembering those eyes in beautiful shades of green and blue, which combine perfectly with their elegant fe...

My parrot itches a lot, what do I do?

All the birds we have as pets bite, this is the true.This also applies to our dear and colorful parrot friends.However, it is important to know that this does not mean that all birds are aggressive or that they have behavioral problems.What it does give us is a little more information in case to consider taking a parrot home.Eventually they will bite you, to the point of believing that your parrot bites you, since with those sharp beaks, it will be painful.However, it is a mistake to talk about bite when it comes to birds, since no teeth are found in its beak. If you have passed that stage and you already have a parrot that you adore but that itches a lot, it is good that you know that this is one of the most common problems observed in "domestic" birds.Parrots are still wild animals, have instinctive features and can bite er for different reasons that you will now know.Although it is very common, itching is a complex problem.So, if your parrot is a bird that repeats thi...

Can you eat shellfish during pregnancy?

Seafood is one of the most exquisite foods out there, but also one of the worst known in the diet of a pregnant woman.Can you eat shellfish and fish during pregnancy? The truth is that it has many benefits for the future breast and the fetus, but as long as the appropriate varieties are chosen, they are cooked well and in a healthy way and not excessive consumption is made.Especially, during this stage, it is essential to avoid consumption of raw fish or shellfish and opt for those varieties with a lower amount of mercury so as not to endanger the health of the baby or the pregnant woman.Read this ONsalus article to know all the details about the issue: Can seafood be eaten during pregnancy? Can I eat shellfish in pregnancy? The fats that seafood has are mostly healthy, in addition to also having omega-3, an element that lowers cholesterol, especially if taken on a regular basis, which also helps decrease the risk of heart disease.Therefore, seafood has very significant benefits ...

Why do cats make a lot of noise when they mate?

If you have seen the mating of two wise cats that do a lot of noise.The truth is that the meows begin when the cats enter into heat, to attract the attention of the males .They also respond with meows and so the procession begins. But it is during the copula that the screams are more obvious and scandalous.Many people wonder why do cats make a lot of noise when they mate? In Animal Expert we will answer your question, you will be surprised. Sexual maturity and zeal Females reach sexual maturity between 5 and 9 months of age.Males, meanwhile, somewhat later, between 9 and 12 months .It is quite evident when cats are in heat.In addition to the characteristic meowing, there are many other signs that a cat is in heat, such as licking, tail lifting, etc. The heat in cats has an average of 5 to 7 days and is repeated once a month .This interval will depend on whether the cat has crossed or not with a male during the heat Other factors that may intervene are the season of the a...

Animals and Pets Online

Search This Blog